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Aseptic diaphragm valve is a fluid control valve designed for food, pharmaceutical, bioengineering and other hygienic sensitive industries. Compared with other sanitary valve designs, this valve is easier to clean and handles materials with particles well. In the application of flow control, there is less cavitation.

In the pharmaceutical industry, the requirements for hygiene and pollution prevention are very high, so it involves fluid handling, clean room environment, CIP/SIP system and other aspects.

The main features of Tank bottom diaphragm valves are no dead angle, easy to clean, high sealing and sterility.

Donjoy aseptic diaphragm valve passes US-3A,CE and FDA certification.

The application scenarios of aseptic diaphragm valves in the pharmaceutical industry mainly include the following aspects

1. Bioreactor and fermenter systems

Used for feeding, discharging and sampling port control of bioreactors such as cell culture and vaccine production.

The sealing structure of the diaphragm valve avoids microbial contamination, and the dead-angle design prevents residues, which meets the GMP requirements for sterile environment.

2. Sampling systems

Aseptic diaphragm valves are used to sample pharmaceutical products at various stages of the production process while maintaining the sterility of the product and the sampling point.

‌3. Aseptic filtration

Aseptic diaphragm valves are used to control the flow of pharmaceutical liquid and gas through aseptic filters to ensure that the filtered products are not contaminated by microorganisms.

Its smooth inner surface and no dead angle design can prevent the accumulation of particles and microorganisms, thereby avoiding affecting the filtration process.

4. Aseptic filling and packaging

Filling pipeline control of injections, ophthalmic preparations and other products to prevent particles from falling off or microorganisms from invading during the filling process.

Aseptic diaphragm valves support online steam sterilization (SIP, above 121℃)

5. Clean utilities

These valves are essential for the distribution systems of ultrapure water (water for injection - WFI), clean steam and other key utilities used in pharmaceutical production.

Their design prevents contaminants from entering these high-purity systems.

6.CIP/SIP system‌

In the pharmaceutical industry, CIP (Cleaning in Place) and SIP (Sterilization in Place) are commonly used cleaning and disinfection methods. The no-dead-spot design and high chemical resistance of aseptic diaphragm valves make them ideal for use in these cleaning and sterilization processes.

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